SSH EN ISO 20776-1:2006

Testimi klinik laboratorik dhe sistemet e provës të diagnostikimit in vitro - Testimi i ndjeshmërisë së agjentëve infektivë dhe vlerësimi i performancës së pajisjeve të provës së ndjeshmmërisë kundër mikrobeve - Pjesa 1: Metoda referuese për provën e aktivitetit in vitro të agjentëve antimikrobial kundër baktereve aerobe me shpejtësi në rritje të përfshira në sëmundjet infektive (ISO 20776-1:2006)

Clinical laboratory testing and in vitro diagnostic test systems - Susceptibility testing of infectious agents and evaluation of performance of antimicrobial susceptibility test devices - Part 1: Reference method for testing the in vitro activity of antimicrobial agents against rapidly growing aerobic bacteria involved in infectious diseases (ISO 20776-1:2006)

Scope

ISO 20776-1:2006 describes one reference method, broth microdilution, for determination of MICs. The MIC reflects the activity of the drug under the described test conditions, and can be interpreted for clinical management purposes by taking into account other factors, such as drug pharmacology or bacterial resistance mechanisms. This allows categorization of bacteria as susceptible (S), intermediate (I), or resistant (R). In addition, MIC distributions can be used to define wild type or non-wild type bacterial populations. Although clinical interpretation of the MIC value is beyond the scope of ISO 20776-1:2006, modifications of the basic method are required for certain antimicrobial agent - bacteria combinations to facilitate clinical interpretation. These modifications are included in a separate table. It is advisable to compare other susceptibility testing methods (e.g. routine methods or diagnostic test devices) with this reference method for validation, in order to ensure comparable and reliable results.

Related directives

Directives related to this standards.