ISO 22634-1:2017 specifies a method for the determination of benzo[a]pyrene (B[a]P) in the total particulate matter of cigarette mainstream smoke using gas chromatography/mass spectrometry (GC/MS) with methanol as extraction solvent.
This method was validated using ISO 3308 smoking parameters and is technically compatible with other smoking regimes.
An alternative method for the determination of B[a]P is specified in ISO 22634‑2 with a different clean-up using cyclohexane solvent and a reduced analytical run.
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