prDS CWA 18308:2025

Evaluation of the mechanism of action of antiviral coated plastics and other coated non-porous surfaces

Scope

This document specifies proper methods to investigate the mechanism of action by which a coated specimen reduces viral infectivity titer. This protocol is intended to be used after the verification of the antiviral activity of a coated surface following the ISO 21702:2019 guideline. Two test procedures are described in this document. The first test, the drying test, aims to evaluate whether the antiviral activity of a coated material is due to the direct inactivation of virus particles. The second one, the ion release test aims to assess the potential indirect antiviral activity of ions released by a coated specimen. Due to the individual sensitivities, the results of one test virus might not be applicable for other viruses.